Biomechanics and Mechanobiology of Heart Failure
The heart failure (HF) subgroup was established in 2018, with a focus on understanding myocardial adaptation to hemodynamic stress (such as in valvular heart disease) at the organ, tissue, cell and sub-cellular levels. We seek to translate this knowledge to clinical application, by developing biomechanical markers of early cardiac dysfunction, and develop technologies that restore physiological biomechanics as a therapeutic target.