PEDIATRIC STRUCTURAL HEART DEFECTS : PATHOGENESIS AND THERAPIES
Structural defects of the heart and vascular system are the most common pediatric cardiovascular conditions treated surgically in children. Our laboratory is interested in the pathogenesis of such structural defects, from their genesis during fetal development, to the optimal approaches to treat or manage such defects. Some defects may be simple that surgical reconstruction may cure them, and our interests are in optimizing the techniques and materials that will yield durable and long-term reconstruction. Some defects may be complex that surgical reconstruction may be palliative only, and our goal in those cases is to develop new therapies and approaches that could be significantly better than available approaches.