STRUCTURAL HEART RESEARCH & INNOVATION LABORATORY
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    • Heart Valve Biomechanics
    • Biomechanics and Mechanobiology of Heart Failure
    • Pediatric Heart Defects
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Innovation and Technology Incubation

As an engineering laboratory integrated into a clinical division, we develop new technologies that may be better or radically new solutions to treat structural heart diseases. These technologies are prototyped, tested, and risk mitigated in our laboratory, and either out-licensed for development or spun off into start-up companies that will seek investment from the market.
CARDIAC LEAFLET ENHANCER
Transcatheter mitral & tricuspid valve repair system 
Patents: US 9510948, US 20200205978  
Status: Advanced pre-clinical, Spun out as Nyra Medical 
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CORACCESS
High frequency ultrasound integrated sheaths to reduce blood loss during access to beating cardiac chambers
Patents: US 10,849,652 
Status: Prototype developed, preclinical proof of concept completed, available for licensing
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CORONARY STABILIZER
Multi element catheter with conformable elements
Patents: US 10,149, 672
Status: Prototype  
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CLINICAL TRIALS

IMPROVE-FMR
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​IMPROVE-FMR: Improving mitral repair for functional mitral regurgitation
Sponsor:
National Heart, Lung and Blood Institute
Clinical trial identifier: NCT03366649
Principal Investigator: Muralidhar Padala PhD
Objective: Observational study to investigate the durability of undersizing mitral annuloplasty in repair of functional mitral regurgitation, and the extent of reverse remodeling of the left ventricle 
Recruiting sites: EUH, EUHM, ESJH
  • Home
  • Research
    • Heart Valve Biomechanics
    • Biomechanics and Mechanobiology of Heart Failure
    • Pediatric Heart Defects
  • Innovation
  • Team
  • Facilities
  • Publications
    • Journal Club
  • Courses
  • News
  • Openings